Select an upcoming Colon cruise itinerary list below to find a Colon sailing itinerary by destination, line, or ship. Search All Cruises Lindblad Expeditions12/06/20267 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98812/13/20267 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98801/13/20278 Night South American Cruise Exploring Arenal Volcano, Pearl Islands and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/17/20278 Night South American Cruise Exploring Arenal Volcano, Pearl Islands and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/21/20278 Night South American Cruise Exploring Arenal Volcano, Pearl Islands and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/29/20277 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,761$10,460$11,559Ponant10/20/202610 Night South American Cruiseon the Ponant L'Austral departing from Colon, PanamaInteriorOceanviewBalconySuite-$5,560$6,070$12,12011/07/20267 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$6,130$9,66011/21/202610 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$10,390$16,36012/18/202610 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,100$10,64012/19/202610 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,260$11,96001/14/202710 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,100$10,64001/15/20277 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/26/20277 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/12/202710 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,260$11,96004/08/202710 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,220$10,640Royal Caribbean International07/04/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$814$884--07/11/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$834$854-$2,53907/18/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$945$962-$2,63907/25/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,069$1,172-$2,43908/01/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$852$984-$1,42808/08/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$874$904-$1,96908/15/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$694$714$1,228$1,82908/22/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$583$622$1,044$1,24908/29/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$676$543$1,616$1,07509/05/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$614$714$1,553$3,19909/12/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$550$560$2,283$1,41909/19/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$480$541$1,179$1,45409/26/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$479$543$1,194$1,07610/03/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$517$525$946$1,16610/10/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$536$546$988$1,15810/17/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$460$470$744$81610/24/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$550$569$826$1,04010/31/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$569$596$1,105$1,61611/07/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$533$569$861$1,10311/14/202610 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$567$630$1,148$1,59912/19/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$838$848$1,393$1,37412/26/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,304$1,487$2,094$3,51901/02/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$856$956$1,489$1,57901/09/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$926$1,046$1,568$1,56901/16/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,231$1,231$1,379$1,56901/23/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,051$1,203--01/30/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$896$936$1,379$1,53902/06/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$790$799$1,228$1,58802/13/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$601$636$1,298$2,00702/20/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$686$936$1,249$1,41802/27/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$706$916$1,409$1,44803/06/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$736$866$1,269$1,37803/13/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$681$781$1,508$1,64903/20/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$846$856$1,389$1,44803/27/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,071$1,116$1,718$1,87904/03/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$755$959$1,519$1,59904/10/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$936$1,046$1,689$1,62804/17/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$829$1,129$1,708$1,728Windstar Cruises12/19/20267 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/19/20267 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,404--01/02/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,104-$6,11401/02/20277 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/05/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,934$5,594$8,42901/05/20277 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/19/20277 Night Central America & Panama Canal Cruise Lima Machu Picchu Pre Cruise Tour to Panamaon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/19/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,934$5,594$8,42901/19/20277 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability